Posted by Steph in
, on Thursday, January 4. 2007 at
Posted by Steph in
Chemotherapy, on Thursday, January 4. 2007 at
To answer all your highly pertinent questions would take an hour of writing
at least -and a good hour of face to face conversation -and maybwe you
should consider a visit here for a formal consultation to do just that!
In the meantime, let me assure you of the following:
1. Your intepretation of what Dr. Etzl described as the plans for the
remaining therapy are correct; 2 cycles of Induction (cycles 4 and 5)
followed by a sinlge cycle of marrow ablative chemotherapy followed by the
blood cell rescue. And NO radiation therapy.
Your nervousness is entirely appropriate -and ALL parents going through this
and other drug treatments of simiar intensity experience this -you would not
be a caring mother if you did not!
"Dose Intensity" implies, as you indicated, 'giving cycles close together'
but also impies how big a dose you receive. Let's put theory adie; your
child's MRI scans and spinal fluid remain clear -indicating how powerful the
first three cycles were at clearing remaining tumor cells and prevernting
recurrence. Yes, there have been iother children with significant delays and
no, this is NOT predictive of subsequent relapse (although of course a
proportion of children do develop recurrence even when the timing is
"optimal"). I would NOT recommend extra induction chemotherapy rounds
because it would be FAR TOO TOXIC! And, ALL children go through 5 induction
cycles, irrespective of extent of resection or dissemination.
If your son develops a recurrence, then his curability depends upon where
the recurrence is located; if localizedv to the original tumor site, then
surgery, followed by some chemotherapy AND IRRADIATION wouild be the ONLY
prospect for cure. Only under very special circumstances have I or others
performed second transplants; it cannot aid in avoiding irradiation at
recurrence: Bottom line -the time to cure this tumor is NOW.
Hang in there!
Best wishes for 2007